The Development of a Systematic Coarse-Grain Model for Polymer Drug Encapsulation
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The Evaluation of High Throughput Apparent Solubility and Conformation Assays as Predictive Tools for Early Stage Formulation Development
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The Development of a Systematic Coarse-Grain Model for Polymer Drug Encapsulation
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Dr. Hanns-Christian Mahler
Roche – hanns-christian.mahler@roche.com Key Interactions of Polysorbates in Protein Formulations Surfactants, such as polysorbates, are frequently used for formulating protein therapeutics. They protect proteins against interface-induced stresses. This includes protection against aggregation and precipitation caused by air/liquid interfaces (e.g. shaking), by ice/liquid interfaces (e.g. freezing and thawing) and against adsorption of protein often observed with […]
Dr. Hanns-Christian Mahler
Roche – hanns-christian.mahler@roche.com Key Interactions of Polysorbates in Protein Formulations Surfactants, such as polysorbates, are frequently used for formulating protein therapeutics. They protect proteins against interface-induced stresses. This includes protection against aggregation and precipitation caused by air/liquid interfaces (e.g. shaking), by ice/liquid interfaces (e.g. freezing and thawing) and against adsorption of protein often observed with […]
Other formulation conferences
245th American Chemical Society National Meeting April 7-11, 2013, New Orleans, Louisiana Division of Colloid and Surface Chemistry (COLL) Symposium on Formulating for Precision at the Nanometer Scale This symposium highlights challenges and progress in developing formulations involving nano-scale components and interactions, with a focus on pharmaceutical, food, and consumer applications. Contributions that specifically address […]
Check out other relevant formulation conferences
245th American Chemical Society National Meeting April 7-11, 2013, New Orleans, Louisiana Division of Colloid and Surface Chemistry (COLL) Symposium on Formulating for Precision at the Nanometer Scale This symposium highlights challenges and progress in developing formulations involving nano-scale components and interactions, with a focus on pharmaceutical, food, and consumer applications. Contributions that specifically address […]
Establishment of Formulation Special Interest Group
An exciting initiative has been taken after consultations across the UK formulation industry by the Technology Strategy Board of the UK Department of Business, Innovation and Skills (BIS) to fund the setting up of a “Formulation Special Interest Group (SIG)” co-ordinated by Chemistry Innovation Knowledge Transfer Network (CiKTN). The establishment of the Formulation Special Interest […]
It’s All In The Mix – 03 The Role of the Baking Process in the Formation of Wafer Structure
The role of the baking process in the formation of wafer structure Ramana Sundara, Nestle Product Technology Centre, UK This research study is based on two precepts: firstly, wafer is foam, a cellular solid of dried gelatinised starch containing gas cells. Secondly, wafer texture is a result of competition between the developing gas phase and […]
It’s All In The Mix – 02 Physical Modification of Hydrocolloids for New Functionality
Physical modification of hydrocolloids for new functionality John Mitchell, Biopolymer Solutions Ltd The hydrocolloid xanthan gum is modified by extrusion processing. The modified material behaves as a polyelectrolyte particle showing excellent dispersibility in water and a strong salt dependence of the dispersion viscosity. Comparison of the temperature dependence of the viscosity with the temperature of […]