8:00 Registration opens
9:00 Opening remarks
Session 1. Molecular interactions in concentrated biopolymers
Chaired by: Nick Darton (Arecor, UK)
9:15 Intrinsic viscosity and other solution properties as indicators of macromolecular conformation, shape and flexibility. José Garcia de la Torre (Universidad de Murcia, Spain)
9:45 Studying proteins and their interactions in concentrated and crowded environments via tracer sedimentation equilibrium and static light scattering. Germán Rivas Caballero (CSIC, Spain)
10:15 Networking session
11:15 Hybrid gelation processes in enzymatically gelled biopolymers: rheology, nanostructure and cellular response. Cécile Dreiss (King’s College London, UK)
11:45 Exhibitors highlight
12:30 Lunch Break, Exhibition and Posters
Session 2. Development of high concentration biologics
Chaired by: Viren Sarin (Eli Lilly, USA)
13:45 Introduction. Viren Sarin (Eli Lilly, USA)
14:00 Protein-protein interactions in monoclonal antibody formulations: Effect on solution viscosity. Devendra Kalonia (University of Connecticut, USA)
14:30 Crowded Solutions of Globular Proteins and Monoclonal Antibodies: pH, Composition and Excipient Effects on Inter-molecular Interactions and Solution Shear Rheology. Jai Pathak (MedImmune, USA)
15:00 Coffee break, Exhibition and Posters
15:30 Discussion panel: Viscosity in development, manufacturing and use of concentrated doses of biologics – key choices & technical and device options
16:15 Protein-protein interactions, viscosity and injectability in multi protein co-formulations comprising Bevacizumab and recombinant HSA. Jens Thostrup Bukrinski (Novozymes, Denmark)
16:45 Concluding remarks