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MIBio 2013 Programme

8:00 Registration opens

9:00 Opening remarks

Session 1. Molecular interactions in concentrated biopolymers

Chaired by: Nick Darton (Arecor, UK)

9:15 Intrinsic viscosity and other solution properties as indicators of macromolecular conformation, shape and flexibility. José Garcia de la Torre (Universidad de Murcia, Spain)

9:45 Studying proteins and their interactions in concentrated and crowded environments via tracer sedimentation equilibrium and static light scattering. Germán Rivas Caballero (CSIC, Spain)

10:15 Networking session

11:15 Hybrid gelation processes in enzymatically gelled biopolymers: rheology, nanostructure and cellular response. Cécile Dreiss (King’s College London, UK)

11:45 Exhibitors highlight

12:30 Lunch Break, Exhibition and Posters

Session 2. Development of high concentration biologics

Chaired by: Viren Sarin (Eli Lilly, USA)

13:45 Introduction. Viren Sarin (Eli Lilly, USA)

14:00 Protein-protein interactions in monoclonal antibody formulations: Effect on solution viscosity. Devendra Kalonia (University of Connecticut, USA)

14:30 Crowded Solutions of Globular Proteins and Monoclonal Antibodies: pH, Composition and Excipient Effects on Inter-molecular Interactions and Solution Shear Rheology. Jai Pathak (MedImmune, USA)

15:00 Coffee break, Exhibition and Posters

15:30 Discussion panel: Viscosity in development, manufacturing and use of concentrated doses of biologics – key choices & technical and device options

16:15 Protein-protein interactions, viscosity and injectability in multi protein co-formulations comprising Bevacizumab and recombinant HSA. Jens Thostrup Bukrinski (Novozymes, Denmark)

16:45 Concluding remarks

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