Malvern Instruments
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Merrow Scientific
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An atomic force microscopy based method for biopharmaceutical stability determination
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GE Healthcare
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Oval Medical Technologies
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TA Instruments
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Susanne Jörg
Novartis Pharma AG, Switzerland – susanne.joerg@novartis.com Special aspects in the pharmaceutical development of protein formats beyond mAbs In the past decades, monoclonal antibodies have become the fastest growing area of biopharmaceutical industry. Currently, alternative protein formats – such as FAbs, scFvs, nanobodies, etc – are under development. These new antibody and therapeutic protein formats come along with […]
Wyatt Technology UK
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Heath Scientific
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Intrinsic viscosity and other solution properties as indicators of macromolecular conformation, shape and flexibility
The way in which biomacromolecules behave in concentrated solutions depends primarily on their structure and the kinds of their interactions. On the other hand, properties in sufficiently dilute solution depend primarily, and are a source of information, on their structure. Furthermore, the concentration dependence of the properties in the dilute regime is an indicator of the interactions that […]