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Dr. Natalia Markova

GE Healthcare – Natalia.Markova@ge.com Use of ITC/DSC for the studies of biomolecular stability and interaction of excipients with proteins Stability of liquid protein formulation is critical for achieving desired therapeutic effect during prolonged storage of biopharmaceuticals. Our ability to predict factors critical to protein stability is limited due to a complex nature of proteins and a […]

Protein Simple

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Dr. Paul A. Dalby

Dept Biochemical Engineering, UCL, London UK – p.dalby@ucl.ac.uk Screen early – fail early: Rapid analytical screens for protein formulation Biophysical analyses are essential for understanding the effect of formulation excipients on protein stability. However, most are not accessible for small quantities of precious materials or for higher-throughput analyses. Microscale and microfluidic platforms are enabling small quantities […]